DNA Methyltransferase 1 (DNMT1)
[ Edit ]
CXXC9; DNMT; MCMT; Cytosine-5 DNA Methyltransferase 1
 HGNC 2976
 MGI 94912
 PubMed 21745816
 RGD 620979
 UniProt P26358
 USCN J244
 Wiki DNMT1
DNA Methyltransferase 1 (DNMT1)
DNA (cytosine-5)-methyltransferases (DNMTs), such as DNMT1, maintain patterns of methylated cytosine residues in the mammalian genome. Genomic methylation patterns are reshaped during gametogenesis and early development and undergo programmed alterations during cellular differentiation. Methylation patterns are responsible for the repression of parasitic sequence elements and the expression status of genes subject to genomic imprinting and X inactivation. Faithful maintenance of methylation patterns is required for normal mammalian development, and aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.A DNMT1 enzyme is thought to be responsible for most of the maintenance as well as the de novo methylation activities occurring in the somatic cells of vertebrates.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ244Hu01 Recombinant DNA Methyltransferase 1 (DNMT1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAJ244Hu21 Monoclonal Antibody to DNA Methyltransferase 1 (DNMT1) WB, ICC, IHC-P, IHC-F, ELISA
PAJ244Hu01 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEJ244Hu ELISA Kit for DNA Methyltransferase 1 (DNMT1) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ244Mu01 Recombinant DNA Methyltransferase 1 (DNMT1) SDS-PAGE; WB; ELISA; IP.
RPJ244Mu02 Recombinant DNA Methyltransferase 1 (DNMT1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAJ244Mu01 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) IWB, ICC, IHC-P, IHC-F, ELISA
PAJ244Mu02 Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEJ244Mu ELISA Kit for DNA Methyltransferase 1 (DNMT1) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a