Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
CELIAC3; CD152; CTLA4; GSE; IDDM12; Celiac Disease 3
 HGNC 2505
 MGI 88556
 RGD 61975
 UniProt P16410
 USCN B230
Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)
CTLA4 is a protein that plays an important regulatory role in the immune system. In humans, the CTLA4 protein is encoded by the CTLA4 gene.CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells.
CTLA4 is similar to the T-cell costimulatory protein CD28, and both molecules bind to CD80 and CD86 on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB230Hu01 Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB230Hu22 Monoclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) WB, ICC, IHC-P, IHC-F, ELISA
PAB230Hu01 Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB230Hu ELISA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB230Mu01 Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB230Mu01 Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB230Ra01 Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB230Ra01 Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a