Cytochrome P450 Reductase (CPR)
POR; CYPOR; P450R; P450(Cytochrome)Oxidoreductase
 HGNC 9208
 MGI 97744
 PubMed 2127933
 RGD 68335
 UniProt P16435
 USCN D312
 Wiki CPR
Cytochrome P450 Reductase (CPR)
By Southern blot analysis of DNA isolated from a panel of 8 independent human-rodent somatic cell hybrids, Shephard et al. (1989) determined that cytochrome P450 reductase is encoded by a single gene located on 7pter-q22. By in situ hybridization to metaphase chromosomes, they refined the localization to 7q11.2.
In 4 unrelated patients with disordered steroidogenesis including a woman with amenorrhea and 3 children with bony features of Antley-Bixler syndrome, Fluck et al. (2004) found mutations in the POR gene. This was somewhat surprising since the affected individuals lacked apparent disorders of bile acid synthesis or drug metabolism, which also requires P450 enzymes, and knockout of POR is embryonically lethal in mice
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD312Hu01 Recombinant Cytochrome P450 Reductase (CPR) SDS-PAGE; WB; ELISA; IP.
Antibodies MAD312Hu21 Monoclonal Antibody to Cytochrome P450 Reductase (CPR) WB, ICC, IHC-P, IHC-F, ELISA
PAD312Hu01 Polyclonal Antibody to Cytochrome P450 Reductase (CPR) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED312Hu ELISA Kit for Cytochrome P450 Reductase (CPR) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD312Ra01 Recombinant Cytochrome P450 Reductase (CPR) SDS-PAGE; WB; ELISA; IP.
Antibodies MAD312Ra21 Monoclonal Antibody to Cytochrome P450 Reductase (CPR) WB, ICC, IHC-P, IHC-F, ELISA
PAD312Ra01 Polyclonal Antibody to Cytochrome P450 Reductase (CPR) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED312Ra ELISA Kit for Cytochrome P450 Reductase (CPR) Enzyme-linked immunosorbent assay