Cytochrome P450 27B1 (CYP27B1)
VDD1, PDDR; CYP1, P450c1; 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase; Cytochrome P450 Family 27 Subfamily B Polypeptide 1
 HGNC 2606
 MGI 1098274
 PubMed 16549446
 RGD 69192
 UniProt O15528
 USCN D539
 Wiki CYP27B1
Cytochrome P450 27B1 (CYP27B1)
CYP27B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position.
This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD539Hu01 Recombinant Cytochrome P450 27B1 (CYP27B1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAD539Hu01 Polyclonal Antibody to Cytochrome P450 27B1 (CYP27B1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD539Mu01 Recombinant Cytochrome P450 27B1 (CYP27B1) SDS-PAGE; WB; ELISA; IP.
RPD539Mu02 Recombinant Cytochrome P450 27B1 (CYP27B1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAD539Mu01 Polyclonal Antibody to Cytochrome P450 27B1 (CYP27B1) IWB, ICC, IHC-P, IHC-F, ELISA
PAD539Mu02 Polyclonal Antibody to Cytochrome P450 27B1 (CYP27B1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SED539Mu ELISA Kit for Cytochrome P450 27B1 (CYP27B1) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD539Ra01 Recombinant Cytochrome P450 27B1 (CYP27B1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAD539Ra01 Polyclonal Antibody to Cytochrome P450 27B1 (CYP27B1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits n/a n/a n/a