Cyclin G Associated Kinase (GAK)
In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cyclin G Associated Kinase (GAK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cyclin G Associated Kinase (GAK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cyclin G Associated Kinase (GAK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cyclin G Associated Kinase (GAK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclin G Associated Kinase (GAK) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cyclin G Associated Kinase (GAK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cyclin G Associated Kinase (GAK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cyclin G Associated Kinase (GAK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cyclin G Associated Kinase (GAK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclin G Associated Kinase (GAK) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cyclin G Associated Kinase (GAK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cyclin G Associated Kinase (GAK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cyclin G Associated Kinase (GAK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Cyclin G Associated Kinase (GAK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Cyclin G Associated Kinase (GAK) | ELISA Kit Customized Service Offer |