Crumbs Homolog 1 (CRB1)

LCA8; RP12

Crumbs homolog 1 is a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye.
Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternatively spliced transcript variants have been observed but their full-length nature has yet to be determined. One small study suggests that mutations in this gene are associated with keratoconus in patients that already have Leber's congenital amaurosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Crumbs Homolog 1 (CRB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Crumbs Homolog 1 (CRB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Crumbs Homolog 1 (CRB1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Crumbs Homolog 1 (CRB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Crumbs Homolog 1 (CRB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Crumbs Homolog 1 (CRB1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Crumbs Homolog 1 (CRB1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Crumbs Homolog 1 (CRB1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Crumbs Homolog 1 (CRB1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Crumbs Homolog 1 (CRB1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Crumbs Homolog 1 (CRB1) ELISA Kit Customized Service Offer