Complement Factor H (CFH)
CF-H; FH; FHL1; ARMD4; ARMS1; CFHL3; HF1; HF2; HUS; H Factor 2; Age-Related Maculopathy Susceptibility 1; Adrenomedullin binding protein
 HGNC 4883
 MGI 88385
 PubMed 9848786
 RGD 620428
 UniProt P08603
 USCN A635
 Wiki Factor_H
Complement Factor H (CFH)
Factor H is a member of the regulators of complement activation family and is a complement control protein. It is a large (155 kilodaltons), soluble glycoprotein that circulates in human plasma (at a concentration of 500–800 micrograms per milliliter). Its main job is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens and does not damage host tissue. Factor H regulates complement activation on self cells by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3 convertase, C3bBb. Factor H protects self cells from complement activation but not bacteria/viruses, in that it binds to glycosaminoglycans (GAGs) that are present on host cells but not pathogen cell surfaces.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA635Hu01 Recombinant Complement Factor H (CFH) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA635Hu22 Monoclonal Antibody to Complement Factor H (CFH) WB, ICC, IHC-P, IHC-F, ELISA
PAA635Hu01 Polyclonal Antibody to Complement Factor H (CFH) WB, ICC, IHC-P, IHC-F, ELISA
PAA635Hu71 Biotin-Linked Antibody to Complement Factor H (CFH) IHC;WB;ELISA
PAA635Hu81 FITC-Linked Antibody to Complement Factor H (CFH) IHC;ICC;IF;WB
Assay Kits SEA635Hu ELISA Kit for Complement Factor H (CFH) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA635Mu01 Recombinant Complement Factor H (CFH) SDS-PAGE; WB; ELISA; IP.
RPA635Mu02 Recombinant Complement Factor H (CFH) SDS-PAGE; WB; ELISA; IP.
Antibodies PAA635Mu01 Polyclonal Antibody to Complement Factor H (CFH) WB, ICC, IHC-P, IHC-F, ELISA
PAA635Mu02 Polyclonal Antibody to Complement Factor H (CFH) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEA635Mu ELISA Kit for Complement Factor H (CFH) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA635Ra01 Recombinant Complement Factor H (CFH) SDS-PAGE; WB; ELISA; IP.
Antibodies MAA635Ra21 Monoclonal Antibody to Complement Factor H (CFH) WB, ICC, IHC-P, IHC-F, ELISA
PAA635Ra01 Polyclonal Antibody to Complement Factor H (CFH) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits CEA635Ra ELISA Kit for Complement Factor H (CFH) Enzyme-linked immunosorbent assay