Coagulation Factor XIII A1 Polypeptide (F13A1)
F13-A1; FXIIIA1; Protein-glutamine gamma-glutamyltransferase A chain; Transglutaminase A chain; Coagulation factor XIII A chain
coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB094Hu01 | Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB094Hu01 | Polyclonal Antibody to Coagulation Factor XIII A1 Polypeptide (F13A1) | WB; IHC; ICC; IP. |
MAB094Hu22 | Monoclonal Antibody to Coagulation Factor XIII A1 Polypeptide (F13A1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB094Hu | ELISA Kit for Coagulation Factor XIII A1 Polypeptide (F13A1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB094Mu01 | Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB094Mu01 | Polyclonal Antibody to Coagulation Factor XIII A1 Polypeptide (F13A1) | WB; IHC; ICC; IP. |
Assay Kits | SEB094Mu | ELISA Kit for Coagulation Factor XIII A1 Polypeptide (F13A1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB094Ra01 | Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB094Ra02 | Recombinant Coagulation Factor XIII A1 Polypeptide (F13A1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB094Ra01 | Polyclonal Antibody to Coagulation Factor XIII A1 Polypeptide (F13A1) | WB; IHC; ICC; IP. |
MAB094Ra21 | Monoclonal Antibody to Coagulation Factor XIII A1 Polypeptide (F13A1) | WB; IHC; ICC; IP. | |
Assay Kits | SEB094Ra | ELISA Kit for Coagulation Factor XIII A1 Polypeptide (F13A1) | Enzyme-linked immunosorbent assay for Antigen Detection. |