Coagulation Factor VII (F7)
FVII; proconvertin; Cothromboplastin; Serum Prothrombin Conversation Accelerator; Stable Factor
 HGNC 3544
 MGI 109325
 RGD 628678
 UniProt P08709
 USCN B874
Coagulation Factor VII (F7)
The main role of factor VII (FVII) is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels - normally not exposed to the bloodstream. Upon vessel injury, tissue factor is exposed to the blood and circulating factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself.
The most important substrates for FVIIa-TF are Factor X and Factor IX. The action of the factor is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent; it is produced in the liver. Use of warfarin or similar anticoagulants impairs its function.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB874Hu01 Recombinant Coagulation Factor VII (F7) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB874Hu22 Monoclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Hu01 Polyclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Hu71 Biotin-Linked Antibody to Coagulation Factor VII (F7) IHC;WB;ELISA
Assay Kits SEB874Hu ELISA Kit for Coagulation Factor VII (F7) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB874Mu01 Recombinant Coagulation Factor VII (F7) SDS-PAGE; WB; ELISA; IP.
RPB874Mu02 Recombinant Coagulation Factor VII (F7) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB874Mu01 Polyclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Mu02 Polyclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Mu71 Biotin-Linked Antibody to Coagulation Factor VII (F7) IHC;WB;ELISA
Assay Kits SEB874Mu ELISA Kit for Coagulation Factor VII (F7) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB874Ra01 Recombinant Coagulation Factor VII (F7) SDS-PAGE; WB; ELISA; IP.
RPB874Ra02 Recombinant Coagulation Factor VII (F7) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB874Ra01 Polyclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Ra02 Polyclonal Antibody to Coagulation Factor VII (F7) WB, ICC, IHC-P, IHC-F, ELISA
PAB874Ra71 Biotin-Linked Antibody to Coagulation Factor VII (F7) IHC;WB;ELISA
Assay Kits SEB874Ra ELISA Kit for Coagulation Factor VII (F7) Enzyme-linked immunosorbent assay