Coagulation Factor VII (F7)
FVII; SPCA; proconvertin; Cothromboplastin; Serum Prothrombin Conversation Accelerator; Stable Factor; Eptacog alfa
The main role of factor VII (FVII) is to initiate the process of coagulation in conjunction with tissue factor (TF). Tissue factor is found on the outside of blood vessels - normally not exposed to the bloodstream. Upon vessel injury, tissue factor is exposed to the blood and circulating factor VII. Once bound to TF, FVII is activated to FVIIa by different proteases, among which are thrombin (factor IIa), factor Xa, IXa, XIIa, and the FVIIa-TF complex itself.
The most important substrates for FVIIa-TF are Factor X and Factor IX. The action of the factor is impeded by tissue factor pathway inhibitor (TFPI), which is released almost immediately after initiation of coagulation. Factor VII is vitamin K dependent; it is produced in the liver. Use of warfarin or similar anticoagulants impairs its function.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB874Hu01 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB874Hu01 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. |
MAB874Hu22 | Monoclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. | |
LAB874Hu71 | Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC. | |
Assay Kits | SEB874Hu | ELISA Kit for Coagulation Factor VII (F7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB874Mu01 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB874Mu02 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB874Mu01 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. |
LAB874Mu71 | Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC. | |
PAB874Mu02 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. | |
Assay Kits | SEB874Mu | ELISA Kit for Coagulation Factor VII (F7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
HEB874Mu | High Sensitive ELISA Kit for Coagulation Factor VII (F7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB874Ra01 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB874Ra02 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APB874Ra02 | Active Coagulation Factor VII (F7) | Cell culture; Activity Assays. | |
RPB874Ra03 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB874Ra01 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. |
PAB874Ra02 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. | |
LAB874Ra71 | Biotin-Linked Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC. | |
Assay Kits | SEB874Ra | ELISA Kit for Coagulation Factor VII (F7) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB874Rb01 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB874Rb51 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. |
PAB874Rb01 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. | |
Assay Kits | n/a | CLIA Kit for Coagulation Factor VII (F7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coagulation Factor VII (F7) | ELISA Kit Customized Service Offer |
Organism species: Bos taurus; Bovine (Cattle)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB874Bo01 | Recombinant Coagulation Factor VII (F7) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB874Bo01 | Polyclonal Antibody to Coagulation Factor VII (F7) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Coagulation Factor VII (F7) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Coagulation Factor VII (F7) | ELISA Kit Customized Service Offer |