Cluster Of Differentiation 40 Ligand (CD40L)
CD154; TRAP; HIGM1; IGM; IMD3; TBAM; T-BAM; TNFSF5; Gp39; TNF Superfamily Member 5; Hyper-IgM Syndrome; TNF-Related Activation Protein; T-Cell B-Cell Activating Molecule
 HGNC 11935
 MGI 88337
 OMIM 300386
 RGD 708418
 UCSC uc004faa.1
 UniProt P29965
 USCN 90119
Cluster Of Differentiation 40 Ligand (CD40L)
Cluster of differentiation 40 ligand(CD40L;CD154) is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In general, CD40L plays the role of a costimulatory molecule and induces activation in APC in association with T cell receptor stimulation by MHC molecules on the APC. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3.
CD40L is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper IgM syndrome.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Organism Manual
E90119HuELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Homo sapiens (Human)  PDF
E90119MuELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Mus musculus (Mouse)  PDF
E90119RaELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rattus norvegicus (Rat)  PDF
E90119SiELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rhesus monkey (Simian)  PDF
E90119CaELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Canis familiaris; Canine (Dog)  PDF
E90119PoELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Sus scrofa; Porcine (Pig)  PDF
E90119BoELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Bos taurus; Bovine (Cattle)  PDF
E90119GaELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Chicken (Gallus)  PDF
E90119FiELISA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rainbow trout  PDF
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Organism Manual
C90119HuCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Homo sapiens (Human)  n/a
C90119MuCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Mus musculus (Mouse)  n/a
C90119RaCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rattus norvegicus (Rat)  n/a
C90119SiCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rhesus monkey (Simian)  n/a
C90119CaCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Canis familiaris; Canine (Dog)  n/a
C90119PoCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Sus scrofa; Porcine (Pig)  n/a
C90119BoCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Bos taurus; Bovine (Cattle)  n/a
C90119GaCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Chicken (Gallus)  n/a
C90119FiCLIA Kit for Cluster Of Differentiation 40 Ligand (CD40L)Rainbow trout  n/a