Caspase Recruitment Domain Family, Member 14 (CARD14)
CARMA2; BIMP2; CARD-containing MAGUK protein 2
CARD14 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure with CARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encoding distinct isoforms have been reported.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Caspase Recruitment Domain Family, Member 14 (CARD14) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Caspase Recruitment Domain Family, Member 14 (CARD14) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Caspase Recruitment Domain Family, Member 14 (CARD14) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Caspase Recruitment Domain Family, Member 14 (CARD14) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Caspase Recruitment Domain Family, Member 14 (CARD14) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Caspase Recruitment Domain Family, Member 14 (CARD14) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Caspase Recruitment Domain Family, Member 14 (CARD14) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Caspase Recruitment Domain Family, Member 14 (CARD14) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Caspase Recruitment Domain Family, Member 14 (CARD14) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Caspase Recruitment Domain Family, Member 14 (CARD14) | ELISA Kit Customized Service Offer |