Caspase 11 (CASP11)
SRSF2IP; SFRS2IP; SIP1; SRRP129; Cysteinyl Aspartate Specific Proteinases 11; Apoptosis-Related Cysteine Peptidase 11; Splicing Factor,Arginine/Serine-Rich 2,Interacting Protein
This enzyme is a member of a family of evolutionarily conserved cysteine protease proteins known as caspases. Many of these enzymes are part of a proteolytic cascade that plays a central role in cell death by apoptosis. Caspase-11 has been isolated and characterized as ICH-3 [ICE and CED3 homolog-3].
Caspase-11 gene expression in response to bacterial lipopolysaccharides and IFN-gamma requires NF-kappa-B and the signal transducer STAT1 .
By performing a yeast 2-hybrid assay to identify proteins that interact with CTD, Tanner et al. (1997) isolated partial cDNAs encoding SIP1, which they called CTD-associated SR protein 11 (CASP11) or SR-related protein of 129 kD (SRrp129). Northern blot analysis detected expression of the approximately 6-kb SRrp129 mRNA in all tissues tested.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog |
Product Name |
Organism |
Manual |
| C90094Hu | CLIA Kit for Caspase 11 (CASP11) | Homo sapiens (Human) | n/a |
| C90094Mu | CLIA Kit for Caspase 11 (CASP11) | Mus musculus (Mouse) | n/a |
| C90094Ra | CLIA Kit for Caspase 11 (CASP11) | Rattus norvegicus (Rat) | n/a |