Caspase 11(CASP11)
SIP1; SRRP129; Cysteinyl Aspartate Specific Proteinases 11; Apoptosis-Related Cysteine Peptidase 11; Splicing Factor,Arginine/Serine-Rich 2,Interacting Protein
 H U G O 10784
M   G   I 1919443
O M I M 603668
R   G   D 1598325
U C S C uc001rox.1
UniProt Q99590
USCNK 90094
Caspase 11(CASP11)
This enzyme is a member of a family of evolutionarily conserved cysteine protease proteins known as caspases. Many of these enzymes are part of a proteolytic cascade that plays a central role in cell death by apoptosis. Caspase-11 has been isolated and characterized as ICH-3 [ICE and CED3 homolog-3]. Caspase-11 gene expression in response to bacterial lipopolysaccharides and IFN-gamma requires NF-kappa-B and the signal transducer STAT1 .
By performing a yeast 2-hybrid assay to identify proteins that interact with CTD, Tanner et al. (1997) isolated partial cDNAs encoding SIP1, which they called CTD-associated SR protein 11 (CASP11) or SR-related protein of 129 kD (SRrp129). Northern blot analysis detected expression of the approximately 6-kb SRrp129 mRNA in all tissues tested.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Species Packing Price Manual
E90094HuELISA Kit for Human Caspase 11(CASP11)Human96T$700   n/a
E90094MuELISA Kit for Mouse Caspase 11(CASP11)Mouse96T$720   n/a
E90094RaELISA Kit for Rat Caspase 11(CASP11)Rat96T$760   n/a
 Antibodies
Catalog Product Name Species Packing Price Manual
A90094HuAntibody to Human Caspase 11(CASP11)Humann/an/a   n/a
A90094MuAntibody to Mouse Caspase 11(CASP11)Mousen/an/a   n/a
A90094RaAntibody to Rat Caspase 11(CASP11)Ratn/an/a   n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Species Packing Price Manual
C90094HuCLIA Kit for Human Caspase 11(CASP11)Humann/an/a   n/a
C90094MuCLIA Kit for Mouse Caspase 11(CASP11)Mousen/an/a   n/a
C90094RaCLIA Kit for Rat Caspase 11(CASP11)Ratn/an/a   n/a