Cardiotrophin Like Cytokine Factor 1 (CLCF1)
CLC; NR6; BSF3; CISS2; NNT1; Novel Neurotrophin-1; B Cell-Stimulating Factor-3
IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure. CLCF1 is closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor.
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia inhibitory factor receptor beta, and the transcription factor STAT3. It has been implicated in the induction of IL-1 (via induction of corticosterone and IL-6) and serum amyloid A, and in B cell hyperplasia. This cytokine is capable of B cell activation via gp130 receptor stimulation.The term "neurotrophin" is commonly used to refer collectively to the four structurally related factors NGF, BDNF, NT-3 and NT-4, while NNT1 bears no structural resemblance to these four proteins.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC389Hu01 | Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC389Hu01 | Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. |
MAC389Hu22 | Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. | |
LAC389Hu71 | Biotin-Linked Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC. | |
Assay Kits | SEC389Hu | ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCC389Hu | CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC389Mu01 | Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC389Mu02 | Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC389Mu01 | Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. |
PAC389Mu02 | Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC389Mu | ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCC389Mu | CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC389Ra01 | Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC389Ra01 | Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. |
MAC389Ra21 | Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) | WB; IHC; ICC; IP. | |
Assay Kits | SEC389Ra | ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCC389Ra | CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) | Chemiluminescent immunoassay for Antigen Detection. |