Cardiotrophin Like Cytokine Factor 1 (CLCF1)
CLC; NR6; BSF3; CISS2; NNT1; Novel Neurotrophin-1; B Cell-Stimulating Factor-3
 HGNC 17412
 MGI 1930088
 RGD 1303171
 UniProt Q9UBD9
 USCN C389
Cardiotrophin Like Cytokine Factor 1 (CLCF1)
IL6 family members share similarity in gene structure and have a 4-helix bundle in their protein structure. CLCF1 is closely related to other proteins called cardiotrophin-1 and ciliary neurotrophic factor.
CLCF1 induces tyrosine phosphorylation of the IL-6 receptor common subunit glycoprotein 130 (gp130), leukemia inhibitory factor receptor beta, and the transcription factor STAT3. It has been implicated in the induction of IL-1 (via induction of corticosterone and IL-6) and serum amyloid A, and in B cell hyperplasia. This cytokine is capable of B cell activation via gp130 receptor stimulation.The term "neurotrophin" is commonly used to refer collectively to the four structurally related factors NGF, BDNF, NT-3 and NT-4, while NNT1 bears no structural resemblance to these four proteins.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC389Hu01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC389Hu22 Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB, ICC, IHC-P, IHC-F, ELISA
PAC389Hu01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB, ICC, IHC-P, IHC-F, ELISA
PAC389Hu71 Biotin-Linked Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IHC;WB;ELISA
Assay Kits SEC389Hu ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay
SCC389Hu CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Chemiluminescent immunoassay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC389Mu01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) SDS-PAGE; WB; ELISA; IP.
RPC389Mu02 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) SDS-PAGE; WB; ELISA; IP.
Antibodies PAC389Mu01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB, ICC, IHC-P, IHC-F, ELISA
PAC389Mu02 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC389Mu ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay
SCC389Mu CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Chemiluminescent immunoassay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC389Ra01 Recombinant Cardiotrophin Like Cytokine Factor 1 (CLCF1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC389Ra21 Monoclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) WB, ICC, IHC-P, IHC-F, ELISA
PAC389Ra01 Polyclonal Antibody to Cardiotrophin Like Cytokine Factor 1 (CLCF1) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC389Ra ELISA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Enzyme-linked immunosorbent assay
SCC389Ra CLIA Kit for Cardiotrophin Like Cytokine Factor 1 (CLCF1) Chemiluminescent immunoassay