Butyrylcholinesterase (BCHE)
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BuChE; CHE1; E1; Pseudocholinesterase; Cholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II
 HGNC 983
 MGI 894278
 PubMed 11848688
 RGD 619996
 UniProt P06276
 USCN C348
 Wiki BCHE
Butyrylcholinesterase (BCHE)
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. Butyrylcholinesterase is believed to play a role in the body's ability to metabolize the drug cocaine. In 2008, an experimental new drug was discovered for the potential treatment of cocaine abuse and overdose based on the BChE structure. It was shown to remove cocaine from the body 2000 times as fast as the natural form of BChE. Studies in rats have shown that the drug prevented convulsions and death when administered cocaine overdoses.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC348Hu01 Recombinant Butyrylcholinesterase (BCHE) SDS-PAGE; WB; ELISA; IP.
RPC348Hu02 Recombinant Butyrylcholinesterase (BCHE) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC348Hu22 Monoclonal Antibody to Butyrylcholinesterase (BCHE) WB, ICC, IHC-P, IHC-F, ELISA
PAC348Hu01 Polyclonal Antibody to Butyrylcholinesterase (BCHE) WB, ICC, IHC-P, IHC-F, ELISA
PAC348Hu02 Polyclonal Antibody to Butyrylcholinesterase (BCHE) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC348Hu ELISA Kit for Butyrylcholinesterase (BCHE) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC348Ra01 Recombinant Butyrylcholinesterase (BCHE) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC348Ra21 Monoclonal Antibody to Butyrylcholinesterase (BCHE) WB, ICC, IHC-P, IHC-F, ELISA
PAC348Ra01 Polyclonal Antibody to Butyrylcholinesterase (BCHE) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits CEC348Ra ELISA Kit for Butyrylcholinesterase (BCHE) Enzyme-linked immunosorbent assay