Butyrylcholinesterase (BCHE)
BuChE; CHE1; E1; Pseudocholinesterase; Cholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. Butyrylcholinesterase is believed to play a role in the body's ability to metabolize the drug cocaine. In 2008, an experimental new drug was discovered for the potential treatment of cocaine abuse and overdose based on the BChE structure. It was shown to remove cocaine from the body 2000 times as fast as the natural form of BChE. Studies in rats have shown that the drug prevented convulsions and death when administered cocaine overdoses.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC348Hu01 | Recombinant Butyrylcholinesterase (BCHE) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPC348Hu02 | Recombinant Butyrylcholinesterase (BCHE) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAC348Hu01 | Polyclonal Antibody to Butyrylcholinesterase (BCHE) | WB; IHC; ICC; IP. |
MAC348Hu22 | Monoclonal Antibody to Butyrylcholinesterase (BCHE) | WB; IHC; ICC; IP. | |
PAC348Hu02 | Polyclonal Antibody to Butyrylcholinesterase (BCHE) | WB; IHC; ICC; IP. | |
Assay Kits | SEC348Hu | ELISA Kit for Butyrylcholinesterase (BCHE) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Butyrylcholinesterase (BCHE) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Butyrylcholinesterase (BCHE) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Butyrylcholinesterase (BCHE) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | CEC348Mu | ELISA Kit for Butyrylcholinesterase (BCHE) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC348Ra01 | Recombinant Butyrylcholinesterase (BCHE) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC348Ra01 | Polyclonal Antibody to Butyrylcholinesterase (BCHE) | WB; IHC; ICC; IP. |
MAC348Ra21 | Monoclonal Antibody to Butyrylcholinesterase (BCHE) | WB; IHC; ICC; IP. | |
Assay Kits | SEC348Ra | ELISA Kit for Butyrylcholinesterase (BCHE) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CEC348Ra | ELISA Kit for Butyrylcholinesterase (BCHE) | Enzyme-linked immunosorbent assay for Antigen Detection. |