Breakpoint Cluster Region (BCR)
ALL; BCR/FGFR1; BCR1; CML; FGFR1/BCR; PHL; Renal carcinoma antigen NY-REN-26
The BCR gene is one of the two genes in the bcr-abl complex, which is associated with the Philadelphia chromosome.A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC328Hu01 | Recombinant Breakpoint Cluster Region (BCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC328Hu01 | Polyclonal Antibody to Breakpoint Cluster Region (BCR) | WB; IHC; ICC; IP. |
Assay Kits | SEC328Hu | ELISA Kit for Breakpoint Cluster Region (BCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC328Mu01 | Recombinant Breakpoint Cluster Region (BCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC328Mu01 | Polyclonal Antibody to Breakpoint Cluster Region (BCR) | WB; IHC; ICC; IP. |
Assay Kits | SEC328Mu | ELISA Kit for Breakpoint Cluster Region (BCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Breakpoint Cluster Region (BCR) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Breakpoint Cluster Region (BCR) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Breakpoint Cluster Region (BCR) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Breakpoint Cluster Region (BCR) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Breakpoint Cluster Region (BCR) | ELISA Kit Customized Service Offer |