BRCA1 Associated ATM Activator 1 (BRAT1)
BAAT1; C7orf27; BRCA1-associated protein required for ATM activation protein 1
BRAT1 Contains 2 HEAT repeats. Ubiquitously expressed. Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM.The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins, including the four name-giving proteins huntingtin, elongation factor 3 (EF3), the 65 Kd alpha regulatory subunit of protein phosphatase 2A (PP2A) and the yeast PI3-kinase TOR1. Arrays of HEAT repeats consists of 3 to 36 units forming a rod-like helical structure and appear to function as protein-protein interaction surfaces. It has been noted that many HEAT repeat-containing proteins are involved in intracellular transport processes. In the crystal structure of PP2A PR65/A, the HEAT repeats consist of pairs of antiparallel alpha helices.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant BRCA1 Associated ATM Activator 1 (BRAT1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant BRCA1 Associated ATM Activator 1 (BRAT1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant BRCA1 Associated ATM Activator 1 (BRAT1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to BRCA1 Associated ATM Activator 1 (BRAT1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for BRCA1 Associated ATM Activator 1 (BRAT1) | ELISA Kit Customized Service Offer |