B-Lymphoid Tyrosine Kinase (BLK)
Tyrosine-protein kinase BLK; p55-Blk
The BLK gene is a nonreceptor protein tyrosine kinase with a calculated molecular mass of about 58 kD. It has an overall amino acid identity of approximately 87% to the mouse Blk; however, in the unique domain of Src family members there is only 58% homology and an insertion of 6 amino acids in the N-terminal region. The nature of this insertion suggested a functional role in membrane attachment. Mutation screening of each exon by direct sequencing of genomic DNA from KWE patients did not reveal any pathogenic mutation. Because BLK is a member of the SRC family, which is thought to play an important role in the signaling pathways controlling cell proliferation and differentiation, the authors considered the gene to be a good positional candidate for the cancers mapping to this region.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE269Hu01 | Recombinant B-Lymphoid Tyrosine Kinase (BLK) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAE269Hu21 | Monoclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | WB; IHC; ICC; IP. |
PAE269Hu01 | Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | WB; IHC; ICC; IP. | |
Assay Kits | SEE269Hu | ELISA Kit for B-Lymphoid Tyrosine Kinase (BLK) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant B-Lymphoid Tyrosine Kinase (BLK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for B-Lymphoid Tyrosine Kinase (BLK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for B-Lymphoid Tyrosine Kinase (BLK) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant B-Lymphoid Tyrosine Kinase (BLK) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for B-Lymphoid Tyrosine Kinase (BLK) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for B-Lymphoid Tyrosine Kinase (BLK) | ELISA Kit Customized Service Offer |