Ataxia Telangiectasia Mutated (ATM)
AT1; ATD; ATA; ATC; ATDC; ATE; TEL1; TELO1; Serine-protein kinase ATM
Ataxia telangiectasia mutated (ATM) is a protein belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB361Hu01 | Recombinant Ataxia Telangiectasia Mutated (ATM) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB361Hu01 | Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | WB; IHC; ICC; IP. |
MAB361Hu22 | Monoclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | WB; IHC; ICC; IP. | |
Assay Kits | SEB361Hu | ELISA Kit for Ataxia Telangiectasia Mutated (ATM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB361Mu01 | Recombinant Ataxia Telangiectasia Mutated (ATM) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB361Mu02 | Recombinant Ataxia Telangiectasia Mutated (ATM) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB361Mu01 | Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | WB; IHC; ICC; IP. |
PAB361Mu02 | Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | WB; IHC; ICC; IP. | |
Assay Kits | SEB361Mu | ELISA Kit for Ataxia Telangiectasia Mutated (ATM) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ataxia Telangiectasia Mutated (ATM) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ataxia Telangiectasia Mutated (ATM) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ataxia Telangiectasia Mutated (ATM) | ELISA Kit Customized Service Offer |