Ataxia Telangiectasia Mutated (ATM)
AT1; ATD; ATA; ATC; ATDC; ATE; TEL1; TELO1
 HGNC 795
 MGI 107202
 PubMed 15824150
 RGD 1593265
 UniProt Q13315
 USCN B361
 Wiki ATM
Ataxia Telangiectasia Mutated (ATM)
Ataxia telangiectasia mutated (ATM) is a protein  belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability.
Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB361Hu01 Recombinant Ataxia Telangiectasia Mutated (ATM) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB361Hu22 Monoclonal Antibody to Ataxia Telangiectasia Mutated (ATM) WB, ICC, IHC-P, IHC-F, ELISA
PAB361Hu01 Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB361Hu ELISA Kit for Ataxia Telangiectasia Mutated (ATM) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB361Mu01 Recombinant Ataxia Telangiectasia Mutated (ATM) SDS-PAGE; WB; ELISA; IP.
RPB361Mu02 Recombinant Ataxia Telangiectasia Mutated (ATM) SDS-PAGE; WB; ELISA; IP.
Antibodies PAB361Mu01 Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) IWB, ICC, IHC-P, IHC-F, ELISA
PAB361Mu02 Polyclonal Antibody to Ataxia Telangiectasia Mutated (ATM) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB361Mu ELISA Kit for Ataxia Telangiectasia Mutated (ATM) Enzyme-linked immunosorbent assay
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a