Aquaporin 4(AQP4)
HMIWC2; MIWC
 H U G O 637
M   G   I 107387
O M I M 600308
R   G   D 2143
U C S C uc002kwa.2
UniProt P55087
USCNK 90582
Aquaporin 4(AQP4)
Aquaporin-4 (AQP4), is a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Aquaporin-4 is located in many tissues, including the basolateral membrane of the renal cortical and medullary principal cell, as well as in the brain.Aquaporin-4 is the first specific molecule to be defined as a target for the autoimmune response in any form of multiple sclerosis. Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells.AQP4 is also expressed in astrocytes and is upregulated by direct insult to the central nervous system.Aquaporin-4 has been proposed as the primary autoimmune target in Devic's disease.
 ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Catalog Product Name Species Packing Price Manual
E90582HuELISA Kit for Human Aquaporin 4(AQP4)Human96T$700   PDF
E90582MuELISA Kit for Mouse Aquaporin 4(AQP4)Mouse96T$720   n/a
E90582RaELISA Kit for Rat Aquaporin 4(AQP4)Rat96T$760   PDF
 Antibodies
Catalog Product Name Species Packing Price Manual
A90582HuAntibody to Human Aquaporin 4(AQP4)Humann/an/a   n/a
A90582MuAntibody to Mouse Aquaporin 4(AQP4)Mousen/an/a   n/a
A90582RaAntibody to Rat Aquaporin 4(AQP4)Ratn/an/a   n/a
 CLIA Kits(Chemiluminescent immunoassay Kits)
Catalog Product Name Species Packing Price Manual
C90582HuCLIA Kit for Human Aquaporin 4(AQP4)Humann/an/a   n/a
C90582MuCLIA Kit for Mouse Aquaporin 4(AQP4)Mousen/an/a   n/a
C90582RaCLIA Kit for Rat Aquaporin 4(AQP4)Ratn/an/a   n/a