Aminolevulinate Delta Synthase 1 (ALAS1)
ALAS3; ALAS
 HGNC 396
 MGI 87989
 RGD 68392
 UniProt P13196
 USCN F209
Aminolevulinate Delta Synthase 1 (ALAS1)
Delta-aminolevulinate synthase 1 is an aminolevulinic acid synthase. Delta-aminolevulinate synthase catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
ALAS1 encodes a housekeeping form of ALAS inasmuch as it is expressed in all cell types, including erythroid cells, whereas ALAS2 encodes a red cell-specific form. ALAS1 and ALAS2 have only 59% identity in amino acid sequence; there was no homology in the amino-terminal region and about 73% homology after hepatic residue 197.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF209Ra01 Recombinant Aminolevulinate Delta Synthase 1 (ALAS1) SDS-PAGE; WB; ELISA; IP.
Antibodies MAF209Ra21 Monoclonal Antibody to Aminolevulinate Delta Synthase 1 (ALAS1) WB, ICC, IHC-P, IHC-F, ELISA
PAF209Ra01 Polyclonal Antibody to Aminolevulinate Delta Synthase 1 (ALAS1) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEF209Ra ELISA Kit for Aminolevulinate Delta Synthase 1 (ALAS1) Enzyme-linked immunosorbent assay