Galactosidase,Alpha(GLa)
GALA; GL-A
Alpha-galactosidase is a glycoside hydrolase enzyme that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It is encoded by the
GLA gene. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry's disease, a rare lysosomal storage disorder and sphingolipidosis that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.
Genzyme produces synthetic agalsidase beta under the brand name Fabrazyme for treatment of Fabry's disease.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
Antibodies
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| A90183Hu | Antibody to Human Galactosidase,Alpha(GLa) | Human | n/a | n/a | n/a |
| A90183Mu | Antibody to Mouse Galactosidase,Alpha(GLa) | Mouse | n/a | n/a | n/a |
| A90183Ra | Antibody to Rat Galactosidase,Alpha(GLa) | Rat | n/a | n/a | n/a |
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog |
Product Name |
Species |
Packing |
Price |
Manual |
| C90183Hu | CLIA Kit for Human Galactosidase,Alpha(GLa) | Human | n/a | n/a | n/a |
| C90183Mu | CLIA Kit for Mouse Galactosidase,Alpha(GLa) | Mouse | n/a | n/a | n/a |
| C90183Ra | CLIA Kit for Rat Galactosidase,Alpha(GLa) | Rat | n/a | n/a | n/a |