Alpha 2-Macroglobulin (a2M)
A2MG; A2mg; CPAMD5
A2MG; A2mg; CPAMD5
-91017.jpg "Alpha 2-Macroglobulin (a2M)")
α2-macroglobulin is a major serum protein with diverse functions, including inhibition of protease activity and binding of growth factors, cytokines, and disease factors. It is also a panproteinase inhibitor that is found immunohistochemically in neuritic plaques
Alpha-2-macroglobulin is able to inactivate an enormous variety of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases).
Alpha-2-macroglobulin has in its structure a 35 aminoacid "bait" region. Proteinases binding and cleaving the bait region become bound to α2M. The proteinase-α2M complex is recognised by macrophage receptors and cleared from the system.
ELISA Kits(Enzyme-linked immunosorbent assay Kits)
CLIA Kits(Chemiluminescent immunoassay Kits)
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| E91017Hu | ELISA Kit for Alpha 2-Macroglobulin (a2M) | Homo sapiens (Human) | |
| E91017Mu | ELISA Kit for Alpha 2-Macroglobulin (a2M) | Mus musculus (Mouse) | |
| E91017Ra | ELISA Kit for Alpha 2-Macroglobulin (a2M) | Rattus norvegicus (Rat) | |
| E91017Rb | ELISA Kit for Alpha 2-Macroglobulin (a2M) | Oryctolagus cuniculus (Rabbit) | n/a |
| E91017Po | ELISA Kit for Alpha 2-Macroglobulin (a2M) | Sus scrofa; Porcine (Pig) | n/a |
| Catalog | Product Name | Organism | Manual |
|---|---|---|---|
| C91017Hu | CLIA Kit for Alpha 2-Macroglobulin (a2M) | Homo sapiens (Human) | n/a |
| C91017Mu | CLIA Kit for Alpha 2-Macroglobulin (a2M) | Mus musculus (Mouse) | n/a |
| C91017Ra | CLIA Kit for Alpha 2-Macroglobulin (a2M) | Rattus norvegicus (Rat) | n/a |
| C91017Rb | CLIA Kit for Alpha 2-Macroglobulin (a2M) | Oryctolagus cuniculus (Rabbit) | n/a |
| C91017Po | CLIA Kit for Alpha 2-Macroglobulin (a2M) | Sus scrofa; Porcine (Pig) | n/a |