Adenine Phosphoribosyltransferase (APRT)
AMP; APRTase
 HGNC 626
 MGI 88061
 RGD 1307758
 UniProt P07741
 USCN C310
Adenine Phosphoribosyltransferase (APRT)
APRTase is an enzyme involved in the purine nucleotide salvage pathway. It functions as a catalyst in the reaction between adenine and phosphoribosyl pyrophosphate (PRPP) to form AMP. APRTase is labeled as EC 2.4.2.7. APRT is functionally related to hypoxanthine-guanine phosphoribosyltransferase (HPRT).Deficiency of APRT in human beings may lead to kidney stones formed of adenine and salts.2,8 dihydroxy-adenine urolithiasis is also known as "adenine phosphoribosyltransferase deficiency".
Defects in APRT are the cause of APRT deficiency; also known as 2,8-dihydroxyadenine urolithiasis. It is an autosomal recessive disease characterized by renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC310Hu01 Recombinant Adenine Phosphoribosyltransferase (APRT) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC310Hu22 Monoclonal Antibody to Adenine Phosphoribosyltransferase (APRT) WB, ICC, IHC-P, IHC-F, ELISA
PAC310Hu01 Polyclonal Antibody to Adenine Phosphoribosyltransferase (APRT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC310Hu ELISA Kit for Adenine Phosphoribosyltransferase (APRT) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a