Adenine Phosphoribosyltransferase (APRT)
AMP; APRTase
 HGNC 626
 MGI 88061
 PubMed 18399692
 RGD 1307758
 UniProt P07741
 USCN C310
 Wiki APRT
Adenine Phosphoribosyltransferase (APRT)
APRTase is an enzyme involved in the purine nucleotide salvage pathway. It functions as a catalyst in the reaction between adenine and phosphoribosyl pyrophosphate (PRPP) to form AMP. APRTase is labeled as EC 2.4.2.7. APRT is functionally related to hypoxanthine-guanine phosphoribosyltransferase (HPRT).Deficiency of APRT in human beings may lead to kidney stones formed of adenine and salts.2,8 dihydroxy-adenine urolithiasis is also known as "adenine phosphoribosyltransferase deficiency".
Defects in APRT are the cause of APRT deficiency; also known as 2,8-dihydroxyadenine urolithiasis. It is an autosomal recessive disease characterized by renal failure. Patients have 2,8-dihydroxyadenine (DHA) urinary stones.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC310Hu01 Recombinant Adenine Phosphoribosyltransferase (APRT) SDS-PAGE; WB; ELISA; IP.
Antibodies MAC310Hu22 Monoclonal Antibody to Adenine Phosphoribosyltransferase (APRT) WB, ICC, IHC-P, IHC-F, ELISA
PAC310Hu01 Polyclonal Antibody to Adenine Phosphoribosyltransferase (APRT) WB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEC310Hu ELISA Kit for Adenine Phosphoribosyltransferase (APRT) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a