Actinin Alpha 2 (ACTN2)

Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins.

Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Studies have also implicated alpha actinin in the binding of cardiac ion channels, Kv1.5 in particular.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA376Hu01 Recombinant Actinin Alpha 2 (ACTN2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA376Hu01 Polyclonal Antibody to Actinin Alpha 2 (ACTN2) WB; IHC; ICC; IP.
MAA376Hu22 Monoclonal Antibody to Actinin Alpha 2 (ACTN2) WB; IHC; ICC; IP.
Assay Kits SEA376Hu ELISA Kit for Actinin Alpha 2 (ACTN2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA376Mu01 Recombinant Actinin Alpha 2 (ACTN2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA376Mu01 Polyclonal Antibody to Actinin Alpha 2 (ACTN2) WB; IHC; ICC; IP.
LAA376Mu71 Biotin-Linked Polyclonal Antibody to Actinin Alpha 2 (ACTN2) WB; IHC; ICC.
LAA376Mu81 FITC-Linked Polyclonal Antibody to Actinin Alpha 2 (ACTN2) WB; IHC; ICC; IF.
Assay Kits n/a CLIA Kit for Actinin Alpha 2 (ACTN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actinin Alpha 2 (ACTN2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Actinin Alpha 2 (ACTN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Actinin Alpha 2 (ACTN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Actinin Alpha 2 (ACTN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Actinin Alpha 2 (ACTN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Actinin Alpha 2 (ACTN2) ELISA Kit Customized Service Offer