Actinin Alpha 2 (ACTN2)
Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins.
Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Studies have also implicated alpha actinin in the binding of cardiac ion channels, Kv1.5 in particular.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA376Hu01 | Recombinant Actinin Alpha 2 (ACTN2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA376Hu01 | Polyclonal Antibody to Actinin Alpha 2 (ACTN2) | WB; IHC; ICC; IP. |
MAA376Hu22 | Monoclonal Antibody to Actinin Alpha 2 (ACTN2) | WB; IHC; ICC; IP. | |
Assay Kits | SEA376Hu | ELISA Kit for Actinin Alpha 2 (ACTN2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA376Mu01 | Recombinant Actinin Alpha 2 (ACTN2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA376Mu01 | Polyclonal Antibody to Actinin Alpha 2 (ACTN2) | WB; IHC; ICC; IP. |
LAA376Mu71 | Biotin-Linked Polyclonal Antibody to Actinin Alpha 2 (ACTN2) | WB; IHC; ICC. | |
LAA376Mu81 | FITC-Linked Polyclonal Antibody to Actinin Alpha 2 (ACTN2) | WB; IHC; ICC; IF. | |
Assay Kits | n/a | CLIA Kit for Actinin Alpha 2 (ACTN2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Actinin Alpha 2 (ACTN2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Actinin Alpha 2 (ACTN2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Actinin Alpha 2 (ACTN2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Actinin Alpha 2 (ACTN2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Actinin Alpha 2 (ACTN2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Actinin Alpha 2 (ACTN2) | ELISA Kit Customized Service Offer |