ATP Binding Cassette Transporter C8 (ABCC8)
ABC-C8; PHHI; MRP8; ABC36; HHF1; HI; HRINS; SUR; SUR1; TNDM2; Sulfonylurea Receptor(Hyperinsulinemia)
ABCC8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD628Hu01 | Recombinant ATP Binding Cassette Transporter C8 (ABCC8) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD628Hu01 | Polyclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | WB; IHC; ICC; IP. |
MAD628Hu21 | Monoclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | WB; IHC; ICC; IP. | |
Assay Kits | SED628Hu | ELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant ATP Binding Cassette Transporter C8 (ABCC8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for ATP Binding Cassette Transporter C8 (ABCC8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant ATP Binding Cassette Transporter C8 (ABCC8) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to ATP Binding Cassette Transporter C8 (ABCC8) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for ATP Binding Cassette Transporter C8 (ABCC8) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP Binding Cassette Transporter C8 (ABCC8) | ELISA Kit Customized Service Offer |