ATP Binding Cassette Transporter B11 (ABCB11)
ABC-B11; BSEP; PFIC2; ABC16; SPGP; PGY4; Progressive Familial Intrahepatic Cholestasis 2; Bile salt export pump
ABCB11 is an ABC transporter named BSEP (Bile Salt Export Pump), or sPgp (sister of P-glycoprotein). This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MDR/TAP subfamily. Some members of the MDR/TAP subfamily are involved in multidrug resistance. This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver cells) to the bile. In humans, the activity of this transporter is the major determinant of bile formation and bile flow.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD641Hu01 | Recombinant ATP Binding Cassette Transporter B11 (ABCB11) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD641Hu01 | Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD641Mu01 | Recombinant ATP Binding Cassette Transporter B11 (ABCB11) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD641Mu01 | Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant ATP Binding Cassette Transporter B11 (ABCB11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to ATP Binding Cassette Transporter B11 (ABCB11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for ATP Binding Cassette Transporter B11 (ABCB11) | ELISA Kit Customized Service Offer |