AT-Rich Interactive Domain Containing Protein 1A (ARID1A)
B120; BAF250; BAF250a; BM029; P270; SMARCF1; SWI/SNF Related,Matrix Associated,Actin Dependent Regulator Of Chromatin,Subfamily F,Member 1
 HGNC 11110
 MGI 1935147
 PubMed 22037554
 RGD 1310500
 UniProt O14497
 USCN K250
 Wiki ARID1A
AT-Rich Interactive Domain Containing Protein 1A (ARID1A)
ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
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Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
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Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a