A Disintegrin And Metalloprotease 17 (ADAM17)
CD156-B; CD156b; TACE; CSVP; Tumor Necrosis Factor,Alpha,Converting Enzyme
 HGNC 195
 MGI 1096335
 PubMed 23441135
 RGD 620404
 UniProt P78536
 USCN B555
 Wiki ADAM17
A Disintegrin And Metalloprotease 17 (ADAM17)
ADAM17 is a 70-kDa enzyme that belongs to the ADAM protein family of disintegrins and metalloproteases.ADAM17 is understood to be involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. This process, which is also known as 'shedding', involves the cleavage and release of a soluble ectodomain from membrane-bound pro-proteins (such as pro-TNF-α), and is of known physiological importance.
ADAM17 was the first 'sheddase' to be identified, and is also understood to play a role in the release of a diverse variety of membrane-anchored cytokines, cell adhesion molecules, receptors, ligands, and enzymes.
Organism species: Homo sapiens (Human)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB555Hu01 Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB555Hu22 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) WB, ICC, IHC-P, IHC-F, ELISA
PAB555Hu01 Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) WB, ICC, IHC-P, IHC-F, ELISA
PAB555Hu71 Biotin-Linked Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) IHC;WB;ELISA
PAB555Hu81 FITC-Linked Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) IHC;ICC;IF;WB
Assay Kits SEB555Hu ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) Enzyme-linked immunosorbent assay
Organism species: Mus musculus (Mouse)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a n/a n/a
Antibodies n/a n/a n/a
Assay Kits n/a n/a n/a
Organism species: Rattus norvegicus (Rat)
CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB555Ra01 Recombinant A Disintegrin And Metalloprotease 17 (ADAM17) SDS-PAGE; WB; ELISA; IP.
Antibodies MAB555Ra21 Monoclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) WB, ICC, IHC-P, IHC-F, ELISA
PAB555Ra01 Polyclonal Antibody to A Disintegrin And Metalloprotease 17 (ADAM17) IWB, ICC, IHC-P, IHC-F, ELISA
Assay Kits SEB555Ra ELISA Kit for A Disintegrin And Metalloprotease 17 (ADAM17) Enzyme-linked immunosorbent assay